Harlowe Life circadian science

THE SCIENCE

科学依据

The research foundation behind a light-first system.

好的光,是有参数的。

Every design decision at Harlowe Life begins with light — a dual-layer architecture of visible rhythm light and an integrated red/NIR support layer. Scent and sound serve as optional supporting layers. Below is the peer-reviewed research foundation behind the system.

每一个设计决策都始于光。可见光层与多光谱层,双层架构。以下是支撑这套系统的参数与研究。

TECHNICAL FOUNDATION

双层光架构

Visible rhythm light above. Integrated red/NIR support layer beneath.

看得见的光之下,还有一层你感受到的。

Every Harlowe light contains two independent but coordinated layers: a visible layer that adjusts color temperature and brightness to follow circadian rhythm, and an integrated red/NIR support layer. Both layers share the same hardware platform and run across the entire Anchor, Axis, and Ritual One collection.

每一盏 Harlowe 都包含两个独立的层:调节色温与亮度的可见光层,和内置的多光谱底层。两层共享同一套硬件。

LAYER 1 — VISIBLE RHYTHM LIGHT 上层 · 可见光

1800K–5000K full spectrum, Ra 97+ color rendering, melanopic-calibrated. Follows the natural arc of the day automatically.

1800K–5500K 全光谱,Ra 97+ 显色指数。跟随一天的自然弧线自动调节色温。

LAYER 2 — INTEGRATED RED/NIR SUPPORT LAYER 底层 · 多光谱

Multiple independent bands covering different tissue depths from surface to deep. Based on peer-reviewed research in the field of photobiomodulation. Full band specifications available on this page.

650nm–950nm 四个独立波段。从红光到近红外,完整覆盖。

650nm

Red

红光

Surface

表层

750nm

Deep Red

深红

Intermediate

中层

850nm

NIR

近红外

Deep

深层

950nm

Far NIR

远近红外

Deepest

最深层

SHARED ACROSS ANCHOR, AXIS, AND RITUAL ONE

ANCHOR、AXIS 和 RITUAL ONE 共享

KEY PARAMETERS — VISIBLE RHYTHM LIGHT

上层 · 可见光参数

Light is the most powerful zeitgeber.

光,是空间里最重要的变量。

Intrinsically photosensitive retinal ganglion cells (ipRGCs) detect melanopic light (peak sensitivity ~480nm) and signal the suprachiasmatic nucleus (SCN) directly via the retinohypothalamic tract — the master clock of the human circadian system. Harlowe's visible rhythm light layer is designed around this pathway.

色温从 5000K 到 1800K 自动过渡。白天是充足的高显色任务光,晚间自动变暖。你不用做任何事。

Morning: Blue-enriched spectrum (5000–5500K) advances circadian phase, supporting natural alertness
Daytime: Full-spectrum Ra 97+ task light, melanopic lux calibrated, providing visual comfort for focused work
Evening: Gradual descent to warm amber (2700K), reducing blue light, permitting natural melatonin onset
Night: 1800K deep amber to full off — minimizing circadian disruption
晨间:富蓝光谱(5000–5500K),充足的光照帮助开启一天
日间:Ra 97+ 全光谱任务光。长时间用眼,依然松弛
傍晚:渐降至 2700K 暖琥珀。蓝光自然减少
夜间:1800K 深琥珀 → 关闭。空间安静下来

Spectrum

光谱

1800K–5500K

Color Accuracy

显色指数

Ra 97+

Transition

过渡

Automatic

自动

Calibration

校准

Melanopic Lux

黑视素勒克斯

Lucas et al., Trends in Neurosciences, 2014

Nature Reviews Neuroscience, 2025

Czeisler et al., Science, 1999

Light dome closeup

INTEGRATED RED/NIR SUPPORT LAYER

底层 · 多光谱

Multiple independent bands. One photobiomodulation foundation.

四个波段。一套完整的多光谱底层。

Photobiomodulation (PBM) is an academic field with decades of research history, studying how specific wavelengths of red and near-infrared light interact with cellular chromophores — particularly cytochrome c oxidase. Harlowe's integrated red/NIR support layer is based on peer-reviewed literature from this field, selecting bands studied for different tissue penetration depths.

四个波段,覆盖从可见红光到近红外。波段选择基于已发表的学术文献。

Part of a general wellness lighting system. Not a medical device.

通用光照系统的一部分。非医疗器械。

650nm

Red Light

红光

Skin surface and superficial tissue

皮肤表面与浅层组织

Absorbed by cytochrome c oxidase near the skin's surface. One of the most extensively studied wavelengths in the photobiomodulation literature, with thousands of peer-reviewed papers examining its interaction with cellular processes.

在光学文献中被广泛研究的波段。数千篇同行评审论文。

Hamblin MR, BBA Clinical, 2016

750nm

Deep Red

深红光

Intermediate tissue depth

中层组织深度

Bridges the gap between visible red and near-infrared. This wavelength has been studied for its ability to reach tissue layers beyond the skin surface while maintaining interaction with cellular chromophores.

可见红光与近红外之间的过渡波段。

de Freitas & Hamblin, IEEE JSTQE, 2016

850nm

Near-Infrared (NIR)

近红外

Deep tissue penetration

深层组织穿透

Invisible to the eye. Penetrates significantly deeper into the body than visible red wavelengths. Extensively studied in the photobiomodulation literature for its interaction with deep tissue layers. This is the primary wavelength behind Harlowe's overnight support mode.

肉眼不可见,穿透更深。Harlowe 夜间模式的主要波段。

Ferraresi et al., Photonics Lasers Med, 2012

950nm

Far Near-Infrared

远近红外

Deepest tissue penetration

最深层组织穿透

At the far end of the near-infrared therapeutic window. Studied for its ability to reach the deepest tissue layers, complementing the 850nm band. Together, the 850nm + 950nm combination provides the broadest deep-tissue coverage in the Harlowe system.

近红外远端。与 850nm 互补,提供最完整的多光谱覆盖。

Hamblin MR, BBA Clinical, 2016; Wunsch & Matuschka, 2014

THE PHOTOBIOMODULATION MECHANISM

光学研究基础

In peer-reviewed literature, the core mechanism of photobiomodulation is described as: specific wavelengths of red and near-infrared light are absorbed by cytochrome c oxidase (Complex IV) in the mitochondrial electron transport chain, interacting with cellular energy processes. This mechanism has been the subject of extensive peer-reviewed research published in journals including BBA Clinical, Photomedicine and Laser Surgery, and IEEE JSTQE.

红光与近红外的光学特性已被广泛研究。相关文献发表于 BBA Clinical、Photomedicine and Laser Surgery、IEEE JSTQE 等期刊。

Harlowe's multi-band architecture is built on this literature base, providing layered support depth within a general wellness lighting system.

Harlowe 的四波段架构基于这一文献基础。

THE DAILY ARC

一天的光弧线

How both layers follow the rhythm of your day.

两层光,跟着一天走。

Morning
MORNING (06:00–09:00) 晨间(06:00–09:00) 1800K → 3500K
Daytime
DAYTIME (09:00–16:00) 日间(09:00–16:00) 5500K
Evening
EVENING (16:00–21:00) 傍晚(16:00–21:00) 2700K
Night
NIGHT (21:00–06:00) 夜间(21:00–06:00) 1800K

MORNING (06:00–09:00)

晨间(06:00–09:00)

VISIBLE RHYTHM LIGHT

可见光层

Gradual sunrise from 1800K → 3500K, increasing melanopic lux

1800K → 3500K 渐进日出

RED/NIR LAYER

红光/近红外层

Red/NIR layer off — daytime begins with visible light only

多光谱层关闭。白天以可见光开始

DAYTIME (09:00–16:00)

日间(09:00–16:00)

VISIBLE RHYTHM LIGHT

可见光层

5500K full-spectrum daylight, Ra 97+, peak melanopic calibration

5500K 全光谱,Ra 97+

RED/NIR LAYER

红光/近红外层

Optional: 650nm red light available as background wellness layer during work

可选:650nm 红光作为背景光层

EVENING (16:00–21:00)

傍晚(16:00–21:00)

VISIBLE RHYTHM LIGHT

可见光层

Gradual descent to 2700K warm amber, blue light reduction

渐降至 2700K 暖琥珀

RED/NIR LAYER

红光/近红外层

650nm + 750nm red bands activate — supporting the transition from work to rest

650nm + 750nm 启动

NIGHT (21:00–06:00)

夜间(21:00–06:00)

VISIBLE RHYTHM LIGHT

可见光层

1800K deep amber → off — minimal circadian disruption

1800K 深琥珀 → 关闭

RED/NIR LAYER

红光/近红外层

Full integrated red/NIR activation — overnight support mode, invisible and silent

全四波段启动。不可见,无声

Both layers work in concert but are independently controlled. Visible light follows circadian rhythm. The integrated red/NIR support layer activates automatically in the evening and overnight.

两层光各自独立控制。可见光层自动调节色温,多光谱层在夜间自动启动。

Lan Series

OPTIONAL SUPPORTING LAYER: SCENT

可选层 · 香氛

Olfactory signals reach the amygdala within 150ms — faster than any other sensory pathway.

嗅觉信号在150毫秒内到达杏仁核——比任何其他感官都快。

Lan Series is an optional scent accessory designed to pair with Ritual One. Four blends for different moments of the day. Within a light-first system, scent plays a quiet supporting role — reinforcing the rhythm signal of light, not replacing it.

兰系列是为 Ritual One 设计的可选香氛配件。四款配方对应一天中的不同时段。在以光为先导的系统中,香氛扮演安静的支持角色——增强光的氛围,而非替代它。

Light comes first. Everything else is supporting.

光是第一位。其他一切都是支持。

Herz, Chemical Senses, 2009

Lillehei & Halcon, J Alt Comp Med, 2014

OPTIONAL SUPPORTING LAYER: SOUND

可选支持层:声音

Sound provides temporal structure for the rhythm signal of light.

声音为光的氛围提供时间结构。

Binaural frequency differences accompany different states through auditory steady-state response (ASSR). Delta frequencies (0.5–4Hz) accompany nighttime rest; Alpha (8–12Hz) accompanies relaxed wakefulness; 40Hz Gamma accompanies focused work. Sound is a temporal companion to light, not an independent intervention.

双耳频差通过听觉稳态反应(ASSR)伴随不同状态。Delta频率(0.5–4Hz)伴随夜间休息;Alpha(8–12Hz)伴随放松清醒;40Hz Gamma 伴随专注工作。声音是光的时间伴侣,不是独立的干预。

Chaieb et al., Front. Hum. Neurosci., 2015; Martorell et al., Cell, 2019

LATEST RESEARCH — 2023–2026

最新研究 — 2023–2026

Published in Nature, Science, and Cell

发表于 Nature、Science 与 Cell

The science of circadian health and photobiomodulation is accelerating. Below are recent findings from the world's highest-impact journals that inform our design decisions.

光照环境与光学研究的科学正在加速发展。以下是来自全球最高影响力期刊的最新发现。

I. LIGHT AS THE MOST POWERFUL ZEITGEBER

一、光与人体环境感知

Effects of light on the circadian clock and mood-related behaviours

Nature Reviews Neuroscience, 2025

Light is the most powerful zeitgeber for the human circadian system, directly influencing the SCN and playing a key role in mood regulation through ipRGC pathways.

光是影响人体作息最重要的环境因素之一,在视觉舒适和情绪调节中发挥关键作用。

Stability, Precision, and Near-24-Hour Period of the Human Circadian Pacemaker

Science, 1999

Established the ~24.2h intrinsic period of the human circadian clock — the foundational measurement that all circadian lighting design builds upon.

确立了人体内在生物钟约24.2小时的周期——光照环境设计的基础参考。

II. PHOTOBIOMODULATION — RED/NIR WAVELENGTHS

二、多光谱研究——红光/近红外波段

Photobiomodulation or Low-Level Laser Therapy

BBA Clinical, 2016

Comprehensive review of photobiomodulation mechanisms: red and NIR wavelengths are absorbed by cytochrome c oxidase, interacting with cellular processes. This is the foundational paper for understanding the science behind wellness wavelengths.

光学研究基础综述:红光和近红外波长与细胞线粒体中的色素蛋白相互作用。这是理解多光谱科学基础的核心论文。

Efficacy of Red and Near-Infrared Light Treatment in Collagen Density Increase

Photomed Laser Surg, 2014

Controlled study examining the effects of red and NIR wavelengths on tissue — part of the growing body of peer-reviewed evidence supporting photobiomodulation applications.

对照研究探讨红光和近红外波长对组织的影响——多光谱应用的同行评审证据体系的一部分。

Low-Level Laser (Light) Therapy on Muscle Tissue

Photonics Lasers Med, 2012

NIR wavelength research examining the effects of 850nm on cellular processes — supporting the scientific basis for near-infrared wellness wavelengths.

近红外波长研究,探讨850nm对细胞过程的影响——支持近红外健康波长的科学基础。

III. NON-PHARMACOLOGICAL CIRCADIAN INTERVENTION

三、非药物光照环境设计

Preventive circadian medicine: improving health with sleep checkups

Nature, 2025

Non-pharmacological circadian approaches — light, behavioral cues, and environmental design — represent a growing area of research interest, exploring the relationship between circadian alignment and overall well-being.

光照环境设计——光、行为信号和环境氛围——是前沿研究的重要方向,关注光照环境与自然作息的关系。

四、中国科学家前沿研究

Light-at-night exposure disrupts prefrontal cortex function and cognitive flexibility

Nature Neuroscience, 2024

罗敏敏(Luo Minmin)— 清华大学脑与智能实验室

研究发现夜间人工光照可能影响前额叶功能。支持 Harlowe 晚间琥珀光设计理念。

Olfactory receptor OR10J5 regulates circadian rhythm via SCN-independent pathway

Cell Metabolism, 2025

于晓(Yu Xiao)— 山东大学基础医学院

嗅觉受体与人体作息密切相关。支持兰系列香氛作为氛围支持层的设计理念。

中国市场语境

这场对话在中国同样迫切

从《三联生活周刊》到《中国科学报》——中国最具影响力的科学传播平台正在聚焦同一议题:光照环境与健康生活方式。

《三联生活周刊》

"拯救睡眠" — 封面故事,第1009期(2018年10月)

"能够影响生物钟的外界信号被称作授时因子,包括运动、温度、饮食、光线等,这其中光的干扰是最强的。"

阅读原文 ↗
《三联生活周刊》

"当代年轻人:上一秒熬夜折损,下一秒睡眠投资"(2026年3月)

"熬夜免不了白天昏沉、注意力涣散、情绪低落、浑身疲惫;但并不妨碍转头就热烈、投入地讨论颈椎枕、床垫、助眠产品。"

阅读原文 ↗
人民日报健康客户端

"光污染:现代人隐形杀手"(2025年11月)

"夜间人工光照对人体作息的影响已被多项国内研究关注。文章呼吁回归自然光照环境。"

数据点:据《2024中国居民睡眠健康白皮书》,28%的中国居民每晚睡眠不超6小时,64%报告睡眠质量不佳。

FOUNDATIONAL REFERENCES

基础文献

The peer-reviewed foundation

同行评审基础

Czeisler CA, Duffy JF, Shanahan TL, et al.

Stability, Precision, and Near-24-Hour Period of the Human Circadian Pacemaker

Science. 1999;284(5423):2177-2181

DOI: 10.1126/science.284.5423.2177 ↗

Berson DM, Dunn FA, Takao M.

Phototransduction by Retinal Ganglion Cells That Set the Circadian Clock

Science. 2002;295(5557):1070-1073

DOI: 10.1126/science.1067262 ↗

Lucas RJ, Peirson SN, Berson DM, et al.

Measuring and Using Light in the Melanopsin Age

Trends in Neurosciences. 2014;37(1):1-9

DOI: 10.1016/j.tins.2013.10.004 ↗

Gooley JJ, Chamberlain K, Smith KA, et al.

Exposure to Room Light before Bedtime Suppresses Melatonin Onset

J Clin Endocrinol Metab. 2011;96(3):E463-E472

DOI: 10.1210/jc.2010-2098 ↗

Hamblin MR.

Photobiomodulation or Low-Level Laser Therapy

BBA Clinical. 2016;6:162-168

DOI: 10.1016/j.bbacli.2016.09.002 ↗

Wunsch A, Matuschka K.

Efficacy of Red and Near-Infrared Light Treatment in Collagen Density Increase

Photomed Laser Surg. 2014;32(2):93-100

DOI: 10.1089/pho.2013.3616 ↗

Ferraresi C, Hamblin MR, Parizotto NA.

Low-Level Laser (Light) Therapy on Muscle Tissue

Photonics Lasers Med. 2012;1(4):267-286

DOI: 10.1515/plm-2012-0032 ↗

de Freitas LF, Hamblin MR.

Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy

IEEE J Sel Top Quantum Electron. 2016;22(3):7000417

DOI: 10.1109/JSTQE.2016.2561201 ↗

Martorell AJ, Paulson AL, Suk HJ, et al.

Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology

Cell. 2019;177(2):256-271

DOI: 10.1016/j.cell.2019.02.014 ↗

Chaieb L, Wilpert EC, Reber TP, Fell J.

Auditory Beat Stimulation and its Effects on Cognition and Mood States

Front. Hum. Neurosci. 2015;9:1-12

DOI: 10.3389/fnhum.2015.00420 ↗

Harlowe Life's light protocols are developed in consultation with chronobiologists and photobiomodulation researchers, and reviewed against current peer-reviewed literature. All design parameters are grounded in published research.

Harlowe Life 的光学参数由专业光学研究团队参与设计,并根据最新同行评审文献进行审查。

Disclaimer: Harlowe Life products are general wellness products, not medical devices. They are not intended to diagnose, treat, cure, or prevent any disease. The wavelength and circadian information presented on this website is based on published peer-reviewed research and is provided for educational purposes only. Individual results may vary. If you have a medical condition, consult your healthcare provider before use. These statements have not been evaluated by the FDA.

免责声明:HarloweLife 产品为一般健康产品,非医疗器械。本产品不用于诊断、治疗、治愈或预防任何疾病。本网站展示的光学参数信息基于已发表的同行评审研究,仅供参考。个人体验可能有所不同。如您有健康状况,请在使用前咨询医疗专业人士。本产品未经国家药品监督管理局评估。